Jason Hope Funds the SENS Foundation’s AGE Breakers Program

Jason Hope donated more than $500,000 to fund anti aging research funding to establish the SENS Laboratory in Cambridge and to jump start the AGE breaker program. The SENS Foundation, headed by Dr. Aubrey de Grey, is currently developing AGE breakers which are treatments and pharmaceuticals that have the ability to catabolize or break down molecules produced by advanced glycation. Glycation occurs due to the bonding of a sugar molecule to a protein or fat molecule, without an enzyme. Enzymes are crucial because they help regulate and control how the molecules bond to one another.

These molecules, known as AGES or advanced glycation end products are waste products that build up within the tissues. Some of the AGEs are benign and others are toxic to the body. The harmful AGEs cause progressive damage and loss of functioning to tissues. Examples of this damage include the ability of elasticity in blood vessels and in the skin.

AGEs are associated with many chronic diseases that are age related such as cardiovascular diseases. In these diseases, damage is caused to fibrinogen, endothelium and collagen. An important example of this is atherosclerosis. The end result of the action of AGES is losing elasticity within the blood vessels. Atherosclerosis is more commonly referred to as hardening of the arteries due to the depositing of fat on the walls of blood vessels. This occurs through the destruction of macrophages that are sent to the cell walls of the arteries by AGEs. The purpose of the macrophages is to clean up and remove waste products such as AGEs that are made of mostly cholesterol. Instead, the AGEs poison the macrophages and fat molecules builds up within the arteries. The arteries lose elasticity, constrict the arteries, and limit the flow of blood throughout the body. Blockage of the arteries can lead to stroke and heart attacks.

References: www.facebook.com/public/Jason-Hope

Omar Boraie Envisions a Prosperous Future for New Jersey Cities

A Vision for New Brunswick

“When we started here in 1972, it was awful.” Says Omar Boraie, President of Boraie Development. He’s reflecting on what others thought was his risky investment in New Brunswick, New Jersey. “You couldn’t walk the streets after 4 p.m. Everyone had left the city. But I thought ‘This is an area where we could do something.’” Omar, trained as a chemist in Egypt, had witnessed the transformation of cities in Europe and believed New Brunswick could be similarly modernized.

 

Albany Towers Built and New Brunswick Takes Shape

Albany Street Plaza Tower One was first, bringing Class A office space to the city. Tower Two came in 2003, adding more Class A office space. Omar’s next idea was a high rise condominium building, filled with amenities. “People thought my dad was nuts to build this New York-Style high rise condominium in downtown New Brunswick.” Says Wasseem Boraie, Omar’s oldest son and Vice President of Boraie Development. The building, completed in 2007, sold out in two months’ time. Omar, however, reminds people that it was critical for Johnson and Johnson, the principal employer, to remain in New Brunswick during that 30-year turnaround. He adds that the mayor, Rutgers University, and New Brunswick Development Corporation, among others, were all critical in building the glistening, prosperous city New Brunswick is today. For more details visit Crunchbase.

 

Investing for the Long Term in N.J. Cities

Boraie Development has a track record of going into cities and making long-term investments that others initially deride. Newark and New Brunswick have benefited from Boraie Development’s foresight. Wasseem Boraie is leading the company to make a similar investment in Atlantic City. Both Wasseem and Omar have a vision for the future of New Jersey cities. Wasseem is investing in Atlantic City as he sees it as an ideal place for millennials to live and work. Omar continues to guide Boraie Development’s work in New Brunswick. Omar believes it could be the new hub of tech and biological sciences. “With this extensive infrastructure,” Omar says, “New Brunswick is clearly primed to be the epicenter of New Jersey’s re-emerging knowledge-based economy.” Check out Press of Atlantic City to see more.

 

Omar Boraie Enjoys Creating A Path of His Own

When asked about how to be successful in real estate, investor David Waronker once said, “Buy real estate where the path exists and buy more real estate where there is no path.” Omar Boraie, Boraie Development, and its success with New Brunswick illustrate that creating a unique path is much more beneficial (and fun). “This is my dream,” Omar says, “My dream has come through the past ten years.”

 

 

Read more: http://www.pressofatlanticcity.com/atlanticcitystory/project-brings-market-rate-housing-back-to-atlantic-city/article_83012371-b555-5f8e-9226-89a42625df0d.html

 

Des Perez – The Most Powerful Woman at Roc Nation

The music industry is truly a giant in the world of business. It is surprising that until recently women were excluded from executive positions at record labels and in other parts of the music industry. It is only in recent years that women were able to push themselves into the backrooms and board meetings of some of the most profitable record labels in the world.

Desiree Perez has known the entertainment world for far more time than most women in the industry. She has been an associate of Jay-Z for over two decades. Jay-Z, whose real name is Shawn Carter, has trust Desiree Perez to handle things such as the recruitment of new athletic talent to tours and events for musical talent.

Currently, Perez is the COO of Roc Nation, Carter’s record label. At the label, Perez’s responsibilities consist of working with talent, arranging tours and events, and making contact within the music industry. During her time at Roc Nation, Perez has had the oppurtunity to work with such musical acts as Mariah Carey, Kanye West, Beyonce, Rihanna and Jay-Z himself.

The success of Jay-Z’s newest album, “4:44”, is partially a success because of Perez. She recently made a 200 million dollar deal with Sprint that enabled subscribers of Sprints cellphone service to download “4:44” for free. A similar deal was reached with Samsung for Jay-Z’s previous work, “Magna Carta Holy Grail.” Both deals made it possible for Jay-Z to sell 1 million units before either album had even been released.

As previously mentioned, Roc Nation is not only a record label, it is also an athletic management agency. Their clients consist of legendary athletes such as Miguel Cotto and Kevin Durant. On March 1st, 2018 Roc Nation announced one of its newest talent acquisitions, Romelu Lukaku.

Learn More: www.instagram.com/des.perez/