Jason Hope Funds the SENS Foundation’s AGE Breakers Program

Jason Hope donated more than $500,000 to fund anti aging research funding to establish the SENS Laboratory in Cambridge and to jump start the AGE breaker program. The SENS Foundation, headed by Dr. Aubrey de Grey, is currently developing AGE breakers which are treatments and pharmaceuticals that have the ability to catabolize or break down molecules produced by advanced glycation. Glycation occurs due to the bonding of a sugar molecule to a protein or fat molecule, without an enzyme. Enzymes are crucial because they help regulate and control how the molecules bond to one another.

These molecules, known as AGES or advanced glycation end products are waste products that build up within the tissues. Some of the AGEs are benign and others are toxic to the body. The harmful AGEs cause progressive damage and loss of functioning to tissues. Examples of this damage include the ability of elasticity in blood vessels and in the skin.

AGEs are associated with many chronic diseases that are age related such as cardiovascular diseases. In these diseases, damage is caused to fibrinogen, endothelium and collagen. An important example of this is atherosclerosis. The end result of the action of AGES is losing elasticity within the blood vessels. Atherosclerosis is more commonly referred to as hardening of the arteries due to the depositing of fat on the walls of blood vessels. This occurs through the destruction of macrophages that are sent to the cell walls of the arteries by AGEs. The purpose of the macrophages is to clean up and remove waste products such as AGEs that are made of mostly cholesterol. Instead, the AGEs poison the macrophages and fat molecules builds up within the arteries. The arteries lose elasticity, constrict the arteries, and limit the flow of blood throughout the body. Blockage of the arteries can lead to stroke and heart attacks.

References: www.facebook.com/public/Jason-Hope

Des Perez – The Most Powerful Woman at Roc Nation

The music industry is truly a giant in the world of business. It is surprising that until recently women were excluded from executive positions at record labels and in other parts of the music industry. It is only in recent years that women were able to push themselves into the backrooms and board meetings of some of the most profitable record labels in the world.

Desiree Perez has known the entertainment world for far more time than most women in the industry. She has been an associate of Jay-Z for over two decades. Jay-Z, whose real name is Shawn Carter, has trust Desiree Perez to handle things such as the recruitment of new athletic talent to tours and events for musical talent.

Currently, Perez is the COO of Roc Nation, Carter’s record label. At the label, Perez’s responsibilities consist of working with talent, arranging tours and events, and making contact within the music industry. During her time at Roc Nation, Perez has had the oppurtunity to work with such musical acts as Mariah Carey, Kanye West, Beyonce, Rihanna and Jay-Z himself.

The success of Jay-Z’s newest album, “4:44”, is partially a success because of Perez. She recently made a 200 million dollar deal with Sprint that enabled subscribers of Sprints cellphone service to download “4:44” for free. A similar deal was reached with Samsung for Jay-Z’s previous work, “Magna Carta Holy Grail.” Both deals made it possible for Jay-Z to sell 1 million units before either album had even been released.

As previously mentioned, Roc Nation is not only a record label, it is also an athletic management agency. Their clients consist of legendary athletes such as Miguel Cotto and Kevin Durant. On March 1st, 2018 Roc Nation announced one of its newest talent acquisitions, Romelu Lukaku.

Learn More: www.instagram.com/des.perez/

Jed McCaleb’s Storied History in Tech

Jed McCaleb founded Stellar Development Foundation along side business partner Joyce Kim in 2014. Stellar was not Jed’s only discovery. Jed McCaleb has also been involved with the creation of several other companies. He created eDonkey2000 and Mt Gox: two innovators in their respective industries.


Stellar is one of his newest business ventures. The company was created in 2014 along-side his business partner Joyce Kim. The duo recognized that the financial market was extremely unfair and are doing everything in their power to correct it. Stellar Development Foundation was founded with the intention of bringing services to low income people: services that are previously reserved for the rich.


Financial advice and investment is expensive, even before you can see a return on your investment the dozens of fees and charges can run your pockets dry. Stellar attempts to link several industries together in a seamless way that eliminates many of these costly fees that are associated with these types of industries.


Stellar links these institutions together by use of cryptocurrencies. The company behaves as a middle man, where it is able to handle tasks that previously would cost a fortune in fees for next to nothing.


Jed McCaleb’s Other Ventures


McCaleb’s former business, Mt. Gox, which was originally intended to be an exchange network for players of an online trading card game, went on to become the first Bitcoin exchange in existence. The company was eventually sold to a Japanese company before going out of business.


eDonkey was the first peer to peer file sharing program to utilize multi-source downloading. The company was founded in 2000 by Jed McCaleb and his partner Sam Yagan. The company lead the way with technology that is now considered standard with all peer to peer file sharing platforms. Modern day torrenting and file sharing follows the model provided by eDonkey.


Overnet was a peer to peer network that expanded on McCaleb’s experiences with eDonkey. At its most active, the network boasted around half a million concurrent users.

Top Forex Broker AvaTrade Review

AvaTrade emerged in 2006 before becoming the leading regulated forex broker today. Forex is difficult to understand with so many trading back and forth with foreign currencies and comprehending time zones around the world. Some people might have a lot of experience in trading, but you won’t become a pro right away with Forex. What AvaTrade will provide for you is tailor-made trading solutions, no matter your previous experience or knowledge with any other forex broker. AvaTrade will also equip you with many resources rather its training traders or their premium educational materials to help you develop your trading skills. On AvaTrade’s educational website, they will provide you with one of kind materials for the advanced trader or even just starting out as a beginner. You have the choice in utilizing their ebook and video tutorials to learn the forex trading strategies step-by-step to make you an expert.


The benefit to this is, once you learn the ins and outs of trading, AvaTrade will help you avoid financial losses that will hit your pocket, in-turn assist you with gaining the highest profit as possible. There are countless of brokers online, and with using AvaTrade, you’re going to know what you’re getting as soon as you use their platform. Many brokers out there do no not give that experience to trade with confidence and ease, however, AvaTrade does well with handling currencies in the country that you reside, so no worries there.

Read more AvaTrade reviews: https://www.warriortrading.com/avatrade-broker-review/

AvaTrade will provide you with best times to trade and will not hesitate to answer any questions you might have pertaining to them. With no robots involved, you will be able to receive the answer to any question when it comes to trading. So If you are considering making a certain trade, AvaTrade is a great platform that sets them apart from the rest.

The Oxford Club: Promoting financial freedom

The Oxford Club is a private, worldwide system of financial specialists and entrepreneurs. It utilizes one of a kind, time-tried speculation procedures and standards to reliably beat the stock market and outperform returns in asset classes. The association’s proposals cover bonds, funds, real estate, valuable metals and monetary forms. The Oxford Club’s main goal is to enable individuals to make exceptional, durable riches, and appreciate a rich life that goes past cash.


The Oxford Club started formally as the Passport Club in 1989. The Club was initially created as a small networking association by William Bonner, the organizer of The Agora Companies, along with other founders. Bill’s objective was to create a private money related club, comprised of speculators interested in finding and sharing business opportunities, both in the United States and worldwide. The creators assumed that the best investment opportunities are discovered through research, and not through predominant media outlets or through Wall Street Brokers.


The Oxford Club has outstanding educational resource known as Investment U, established in 1999. Investment U was one of the first free monetary instruction sites. This site offers instructive assets including courses, recordings and meetings, among different assets, with the goal of helping individuals become financially educated and independent. Investment U offers a free e-letter and a top notch adaptation of the e-letter containing daily noteworthy stock suggestions to benefit subscribers.


The Oxford Club’s plan of action can be seen better by taking a glimpse of its enrollment benefits. The Club offers venture data, however this goes beyond giving professional stock and bond suggestions. The Oxford Club members are a piece of an exceptionally remarkable club experience. Oxford Club membership benefits include networking, monthly newsletters, clubhouse access, access to global outposts, and unlimited access to the club’s investment strategies and recommendations.


All You Need to Know About Siteline Cabinetry

Siteline Cabinetry is a furniture company which deals with the manufacture of cabinets. They produce a wide variety of well-crafted full-access cabinets designed to fit the styles of any building’s decor. The company focuses not only on the production of quality, durable, and customized products but also selling their products at affordable prices. Through their skilled staff, they create client specific cabinets on order basis because they do not have a rented or owned warehouse. Siteline Cabinetry also produces products whose styles range from old-fashioned to modern depending on the buyer’s preferences.


Siteline cabinetry gives buyers priority to customize every aspect of the products ranging from materials used, finishes, color and drawer types. The company has invested in manufacturing equipment by using the latest machines to produce quality goods that are not only safe but also long-lasting. It has an efficient manufacturing system which enables the production of the cabinets to be fast and convenient. Siteline Cabinetry also provides a limited lifetime warranty on its products to the original owner by replacing the defective products or fixing them.


About Siteline Cabinetry

Siteline Cabinetry is a recent establishment brand under The Corsi Group Company which was founded by Pat Corsi. It is based in Keysville, Virginia and is recognized for its quality products which are very attractive and suitable to fit the style any room in any building including homes and offices. The company uses a variety of materials to produce the cabinets ranging from wood, veneers, and particleboard to deliver the best goods it possibly can.

The company sells their products exclusively through authorized dealers like the Luxcraft Cabinets with design experts who help in customizing them in ways that perfect their appearance and effectiveness. It has been doing well due to its affordable pricing and life-long warranties making it very competitive in the market. The founder is optimistic about the company’s future expecting it to increase its production while still prioritizing quality of the products it creates.

More on Siteline Cabinetry: http://chronicleweek.com/2017/10/siteline-cabinetry-offers-the-newest-kitchen-cabinet-solution/

Bob Reina: Your Heart Will Show You The Way

When it comes to living a good life and being happy, it might sound cliché, but it is true: follow your heart. When you do that, you start to realize that anything is possible for you. You also have to be willing to take the lumps that come with life. No matter who you are or where you come from, you will have some roadblocks and obstacles thrown in your direction. It is the price that people pay if they want to get ahead and it is just the facts of life. No is immune from hard times and no one is going to be able to go through their life without facing some hard times. It is how they respond to them that is going to define them for their future.


Bob Reina knows this and he wants to impart this wisdom to others that are looking to learn a thing or two about life. He knows you must never give up, no matter how difficult it is. Too often, people are so quick to quit on something because it is too hard and too challenging. In Bob Reina’s eyes, you have to keep at it, no matter how hard it is. There is always a silver lining and every single thing in life is a learning experience for everyone involved, both good and bad.


It is what you do with that experience that shapes you as a human being. You either decide to let it make you or break you. Bob Reina’s Talk Fusion is the company that is going to help people. It is going to show them a different way, and it is going to show them a better way in life. It is the two-time award winning video app company with video newsletters and video chats. Video newsletters are a great way to reach as many people as possible without any issues. You can let people know about your product, and the more that people know about it, the more it can gain steam and get attention. Learn more: https://medium.com/@bobreinatalkfusion/i-challenge-you-to-do-more-9b2cc398dbee


In today’s world, you either get ahead or you get left in the background. If you are smart, you get ahead and you use everything that is out there, specifically Talk Fusion, to your advantage. By doing this, you ensure you will stay ahead and you will also have built a foundation for long-term success.








Sussex Healthcare: Special Announcement And General Information

This will give information about Sussex Healthcare and their special new announcement. On December 21st 2017, a Chief Executive Officer or CEO Amanda Morgan-Taylor. This new addition happened in January 2018. However, she has already contributed work to the team. This is good because she wanted to make herself familiar with every service and home of Sussex Healthcare. This is also including every facet of the work done at that place.

The future job life of Morgan-Taylor has had a focus on positions s of senior leadership. For example, Managing Director, Quality Development Director, and a Service Manager as well. Also, in the past she has spent thirty years with an experience with working in sectors that were in independence and the public.

Read more on weeklyopinion.com

Even before beginning this job, she has shown a great spirit already. For example, she has worked with the team of senior management in order to appoint a new Director in the fields of Service, Compliance, and Quality. Morgan-Taylor, so far in her job life has been working for independent providers of care and in local authorities. Doing this gave her a powerful understanding of relationships with providers and also the council. According to medium.com she has also gained much experience in assisting organizations to do three things build back trust and confidence with stakeholders, bring standards that are consistently high, and talk trust and confidence with stakeholders. Finally, apart of what Amanda will be doing is taking part in visitations of all services and homes and is looking forward to interacting with colleagues, residents, and relatives.

Now some general information regarding Sussex Health Care. This company is located the United Kingdom, Horsham, and West Sussex. This company has been in service since March 1998. This company mainly focuses on offering a group of services which focus on care for people of an older age. An example is a group of people who have mental illnesses such as Alzheimer’s Disease or dementia. It also assists specialist care for adults who have learning or physical difficulties like people who have disabilities that are neurological. Sussex Health Care, like many companies, has a mission. For them two important components of their quality strategy are training and education. This company has a belief that the great service they give goes down to the people who they employ. They have a strong belief in the investment in people to have their potential fulfilled.

For more information about Sussex Healthcare, just click here.

Rodrigo Terpins’ Success on the Tracks

Rodrigo Terpins is one of the best rally drivers to come from Brazil. He is part of the Bull Sertoes Rally Team.

Before being a rally driver, Rodrigo Terpins worked for T5 Partipacoes. He is the senior director of the company and was able to juggle his time between planning some of the largest competitions in Brazil and making the company grow profitably. Prior to his employment with T5 Partipacoes he was the president of Lojas Marisa. You can visit mundodomarketing to see more.


Despite his busy schedule with the said companies, Rodrigo Terpins was still able to build his career on the race track. His passion for this particular sport gave him the ability to maneuver rough terrains in the course of a competition that gave him the opportunity to win and get many awards. His success on the track is fueled by his passion, hard work and perseverance, along with assistance he gets from his partner and co-driver.

Rodrigo Terpins devoted his childhood time in fixing cars, which is what sparked his flair for rallies. Terpins’ role models are his father and brother Michael, who is also a race car driver, a well-known figure in the rally driving scene in Brazil. His father, on the other hand, is the Latin American Jewish Congress President. Both men have guided and supported Rodrigo in his career as a race car driver. For more details visit Crunchbase.

According to Terpins, he considers his career in sports as unique because he can take the pleasure of spending his time by doing what he loves most and working at the same time. Rodrigo says that the occupation he is in entails experience, patience, and discipline.


See more: https://www.terra.com.br/noticias/dino/rally-dos-sertoes-michel-terpins-e-maykel-justo-abrem-vantagem-de-2h-e-seguem-lideres-na-prototipos-t1,54bd7cb0f5c5c9af717c8be93fc5d9afbnagcihv.html



In his Facebook account, Terpins posted that he would not be the success he is today if not for his friend who is also a skilled professional driver. This friend has fans in the thousands who show up during competitions to cheer him on and encourage him to do his best.



Rodrigo Terpins has won in various rally competitions, which also included the T1 prototypes. His name is well known in Minas Gerais and Goias and is expected to be listed as one of the rally legends in Brazil.


Celebrating Achievements By Going To Roberto Santiago’s Mall

For people that work hard and achieve some goal, one of the best things they can do is celebrate their achievements. This not only brings them a lot of joy for their accomplishments, but also motivates them to keep working for their goals. One of the best places to go for self reward is Manaira Shopping, the mall that has been built and constantly enhanced by Roberto Santiago. There are a lot of different ways to celebrate different goals. It depends on the types of goals that people that have been reached. Manaira Shopping is so big and varied that people can have different celebrations for different goals.


For people that have gotten themselves in better shape with all of the hard work, there are clothing stores that have special types of clothing and styles that can show off the newly sculpted body. This can not only help anyone find the most flattering outfit, but can also help each individual feel his or her best. People will have a good feeling about themselves and their achievements that will carry over to other aspects of their lives. People who know how to carry themselves will become very attractive. Manaira Shopping can help people carry themselves as well as they want.


People who have earned a lot of money with their business can celebrate with many different methods. For instance, they can buy some new equipment that will increase their business. Another thing they can do at Manaira Shopping is take advantage of all of the arcades, lounges, and other activities. One can even run a celebration event at one of the restaurants. One of the best things about Manaira Shopping is that there are not only discount fast food places, but also some of the higher quality gourmet companies.


Manaira Shopping is a very unique location. The environment is one of the best environments to experience for people who are looking for a place to shop. For people that want to feel safe and excited, Manaira Shopping from Roberto Santiago has a ton of stores and items to explore. Creativity is encouraged at this establishment.